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Study of High-Risk Drug Use Settings for HIV Prevention
Research Method: Basic Research
Principal Investigators: Margaret R. Weeks, Ph.D. (PI), Jean J. Schensul, Ph.D. (Co-PI), Merrill Singer, Ph.D., HHC (Co-PI)
Grant: National Institute on Mental Health and the National Institute on Drug Abuse (#U01 DA07284, Project #3). Grantee - Yale University Center for Interdisciplinary Research on AIDS
Partners: Hispanic Health Council, Yale University Center for Interdisciplinary Research on AIDS
Dates of Study: 1997-2001

Abstract
Research world-wide indicates that behaviors among active drug users that places them at risk of HIV infection are driven by a combination of individual, physiological, interpersonal, community and social contextual issues. The majority of HIV intervention models up to the early/mid 1990's focused on community education and outreach, and on changing individual beliefs, attitudes and risk behaviors of injection drug users (IDUs). While these approaches had significant impact, research indicated that a focus on individual behavior change did not endure over time. Further community outreach approaches reached only some, but certainly not all of those at highest risk of exposure to HIV infection. New models were needed to reduce opportunities for risk exposure directly, in the social contexts in which infection among IDUs is transmitted.

This three-year, ethnographic study addressed this gap in knowledge by identifying and learning about the locations in which individuals inject and/or smoke illicit drugs and exchange sex for money or drugs. It took the position that characteristics of these locations might heighten risk of exposure. If they could be identified, they could be addressed, thus reducing risk of HIV infection at drug use sites. Through observation, formal and informal interviews, documentation, and surveys, the study explored the variations in types of activities, structures and social relations constituting these "high-risk" sites. Special emphasis was placed on the dynamic process of site creation, modification, dissolution, and reconstitution, to understand the factors influencing this process over time, and the points at which risk might be highest and intervention opportunities might occur. In addition, the project explored and analyzed characteristics of site users' personal networks to assess the viability of a site-and-network-based, peer-led intervention program. Study results led to a subsequent grant, "HIV Prevention in High-Risk Drug Use Sites: Project RAP."

The study was one of four research projects funded under a joint program between the National Institute of Mental Health and the National Institute on Drug Abuse, which established the Yale University Center for Interdisciplinary Research on AIDS (CIRA) and furthered the AIDS prevention research programs of the Institute for Community Research and the Hispanic Health Council. Through this structure, the resources of Yale University became available to the Hartford AIDS research and intervention community; and the knowledge acquired through prior years of investigation and intervention in Hartford were shared with the small but growing Yale AIDS research community.

Project Goals and Objectives
Document the range of variation in structures, social relations, and natural histories of high-risk drug use settings in targeted neighborhoods of Hartford, CT.
Describe and analyze over time the properties of high-risk site users' personal risk networks, including changes in shared risk and preventive behaviors, network density and stability, and changing pathways for diffusion of HIV-risk or prevention effects.
Assess the degree to which high-risk site gatekeepers (e.g., housemen or dealers) and site users are receptive to on-site prevention activities.
Assess the potential for diffusion of benefits of a place-based, peer-leader intervention for HIV risk reduction within and beyond high-risk settings.
Project Details/Research Findings
The project was completed in 2001. During the course of the three-year study, project staff visited and conducted observation of 85 drug-use sites in Hartford, and surveyed a total of 293 drug users. Ethnographic observation and formal/informal interviewing, combined with the survey, provided information on patterns of drug use, drug-use site characteristics, and presence of prevention materials at these locations. Over half of the study participants' primary and secondary sites were public (abandoned buildings, parks, etc.). Private sites were mostly homes or apartments of users, close acquaintances, friends or friends' contacts. Research results showed a greater presence of prevention materials in private sites as compared to public sites; while this indicates a greater potential for prevention behavior, it does not necessarily guarantee that these settings are less risky.

A key finding from the study was the unstable nature of drug use sites. Project staff originally identified 14 sites (10 public, 4 private) for long-term observation. Within two weeks, two of the sites were no longer available, forcing staff to select new locations for observation. Sites continued to become unavailable throughout the project, making long-term site observation difficult. However, documenting and understanding the instability of both private and public sites was a key finding in itself. The study also examined the characteristics of drug-using networks within the city and their relationship to particular sites. Results showed a difference in network characteristics based upon ethnic groups, reaffirming the need for ethnic and culturally appropriate messages and intervention strategies. Network analyses also demonstrated a significant level of peer influence within networks, confirming the potential for an effective peer-based HIV-prevention program. The study resulted in a subsequent intervention grant, "HIV Prevention in High-Risk Drug Use Sites: Project RAP" that is currently testing a peer-led, place-based HIV prevention program, working with many of the participants from this study.

Project Contact:
Margaret R. Weeks, Ph.D., Principal Investigator
Associate Director, ICR

Jean J. Schensul, Ph.D.,

Co-Principal Investigator
Executive Director, ICR

Project Staff:
ICR
Margaret R. Weeks, Ph.D.

Project Director


Jean J. Schensul, Ph.D.

Co-Project Director


Kim Radda, M.A., R.N.

Project Coordinator


D. Scott Wilson, Ph.D.

Project Ethnographer


Maria Martinez, H.S.

Outreach Worker


Robert Rooks, MSW

Project Coordinator (2)

HHC
Merrill Singer, Ph.D.

Co-Project Director


Delia Easton,

Project Ethnographer


Scott Clair, Ph.D.

Statistical Data Analyst


Glenn Scott

Outreach Worker

Yale University
Michael Mersen, M.D., CIRA Principal Investigator


Kim Blankenship, Ph.D., Co-Project Director


Robert Heimer, Ph.D., Collaborator

Link to Research Methods page

Links to other ICR projects:

HIV Prevention in High-Risk Drug Use Sites: Project RAP

External Links:
Hispanic Health Council
Yale University Center for Interdisciplinary Research on AIDS